Induced pluripotent stem cells (iPSC) are the focus of research efforts to create novel cell or tissue therapies that combat neurodegenerative disease, vision impairment, and heart damage. Successful research and translation of iPSC-based therapies is dependent on pairing robust and consistent cell expansion and differentiation protocols with sensitive methods for cell or tissue characterization. Using iPSC-derived neurons and iPSC-derived cardiomyocytes as examples, this webinar discusses tools to help researchers manage iPSC variability, optimize cell differentiation, monitor and characterize differentiation efficiency, and translate their protocols towards clinical application.
Topics covered in this webinar include:
- Tools to evaluate pluripotency and iPSC variability
- Reagents to optimize iPSC differentiation
- Methods to monitor differentiation efficiency (Luminex® and Single-cell Westerns)
- Reagent considerations when translating a protocol from research to the clinic
Scott Schachtele, Ph.D.
Product Manager, Cell Culture and Regenerative Medicine
Scott Schachtele is a Product Manager for the Cell Culture and Regenerative Medicine portfolio at Bio-Techne. Scott works closely with the research teams at Bio-Techne and with industry partners to develop and offer innovative solutions that support cell, gene, and regenerative therapy manufacturing. Scott received his Ph.D. in Neuroscience and joined Bio-Techne in 2014.